• Calendar
• Apply for Workshop
• Workshops
• Visiting Lecturer Program
• Colloquia/Seminars
• Summer Programs
• Public Lectures
• Visitor Info
• Annual Programs
• Propose MBI Programs

Current Topics Workshop: Enzyme Dynamics and Function (May 19-21, 2005)

(Cosponsored by the College of Medicine at The Ohio State University)

Organizers: Russ Hille and Ming-Daw Tsai

Over the past several years, it has become increasingly appreciated that the dynamic properties of enzymes can play a significant role in modulating their catalytic properties. The motions involved can range from the vibration of individual chemical bonds or groups of bonds (taking place on the femtosecond timescale and involving distances of less than 1 A) to large domain motions (taking place on a timescale of milliseconds to seconds and involving distances as great as 10 A or more). With the accumulating experimental evidence attesting to the importance of these motions in catalysis, it has become important to develop appropriate mathematical models for enzyme behavior that provide a conceptual framework within which to understand the influence of this dynamic behavior. The MBI workshop on Enzyme Dynamics and Function will bring together leaders in this emerging field to present their recent work and to participate in discussion groups that will provide a forum for both mathematicians and enzymologists to consider the fundamentals relevant to the field.