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Workshop 2 Schedule
All talks will take place in the MBI Lecture Hall (Math Building Room 240) unless noted otherwise.

Monday, October 2

Metabolic and Neurohumoral Regulation of Excitation and Contraction
8:30-9:00am Coffee and Registration
9:00-9:15am Welcome and Introduction: Avner Friedman, Jim Keener, and Andrew McCulloch
9:15-10:00am Brian O'Rourke: Cardiac Mitochondrial Function and Energetics
10:00-10:15am Coffee Break
10:15-11:00am Miguel Aon: The heart cell viewed from the mitochondrial network: Scaling mitochondrial dynamics to arrhythmias
11:00-11:15am Coffee Break
11:15-12:00pm Anushka Michailova: Adenosine Nucleotides and Lewis Acids Regulate Cardiac Excitation-Metabolic Coupling
12:00-1:30pm Lunch Break
1:30-2:15pm Daniel Beard: Computational Modeling of Oxygen Transport and Cellular Energetics Explains Observations on In Vivo Cardiac Oxygen Consumption and Energy Metabolites
2:15-2:30pm Coffee Break
2:30-3:15pm R. John Solaro: Regulation of Cardiac Dynamics at the Level of Sarcomeric Proteins
3:15-3:30pm Coffee Break
3:30-4:15pm Jeffrey Saucerman: Beta-Adrenergic signaling and regulation of the heart
5:00-7:00pm Reception held in Math Tower, Room 724

 

Tuesday, October 3

Cardiac Muscle Contraction
9:00-9:45am Pieter de Tombe: Myofilament Length Dependent Activation and the Frank-Starling Law of the Heart
9:45-10:00am Coffee Break
10:00-10:45am J. Jeremy Rice: An ODE-based myofilament model approximates spatially-dependent cooperative mechanisms and crossbridge cycling
10:45-11:00am Coffee Break
11:00-11:45am P. Bryant Chase: Crossbridge Mechanics
11:45-1:15pm Lunch Break
1:15-2:00pm Paul Janssen: Frequency dependence of cardiac muscle contraction and relaxation
2:00-2:15pm Coffee Break
2:15-3:00pm Henk ter Keurs: Arrhythmogenic spontaneous sarcomere activity in CHF
3:00-3:15pm Coffee Break
3:15-4:00pm Amir Landesberg: Crissbridge Cycle
6:30pm Public Lecture Series
Jim Keener: Heart Attacks can give you Mathematics
Location: Wexner Center Film/Video Theatre, 1871 North High Street

 

Wednesday, October 4

 

Thursday, October 5

Modeling Cardiac Mechanics
9:00-9:45am Larry Taber: Biomechanics of Cardiovascular Development and Functional Adaptation
9:45-10:15am Coffee Break
10:15-11:00am Theo Arts: Using rules for adaptation to mechanical load in patient-specific modeling of heart and circulation
11:00-1:00pm Lunch Break
1:00-1:45pm Natalia Trayanova: Mechanoelectric Feedback in the Intact Heart
1:45-2:00pm Coffee Break
2:00-2:45pm Julius Guccione: Modeling Cardiac Mechanics: Surgical Interventions
2:45-3:00pm Coffee Break
3:00-4:00pm Panel Discussion
6:00-8:00pm Dinner at the Holiday Inn on the Lane


Friday, October 6

The Intact Heart
9:00-9:45am Alistair Young: Image-derived Cardiac Models
9:45-10:00am Coffee Break
10:00-10:45am Igor Efimov: Optical Mapping of Cardiac Electrical Acitivity
10:45-11:00am Coffee Break
11:00-11:45pm Nicolas Smith: Modeling Coronary Perfusion
 

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