MBI Logo
MBI Logo

Workshop 5: Real Time Brain Interfacing Applications (May 12-15, 2008)

Organizers: Dawn Taylor and David Terman

The field of neural engineering has been transformed by the growth in computer processing power in the last several years. It is now possible to read in multiple neural signals, process those signals, and respond to that processed data in real time. The capability to interact with the nervous system in real time has great potential for the development of new treatments for neurological disorders as well as enabling new experimental studies to further our understanding of the nervous system. For example, areas where real-time interaction can result in improved therapies or treatments include:

  • Direct brain control of assistive devices for the paralyzed
  • Closed-loop control of deep brain stimulation (DBS) (e.g., for Parkinson's disease)
  • Prediction and intervention of epileptic seizures
  • Closed-loop stimulation of paralyzed nerves to restore function

This real-time interaction posses special challenges because device design requirements often include minimizing power consumption and device size for implantation. This necessitates implementing efficient algorithms and quantifying the tradeoffs between making algorithms more efficient verses more effective. Another issue common to most chronic neural engineering applications is non-stationarity of the neural interface and of the biological system itself.

The themes of the workshop will include: spike sorting and tracking; cortical decoding of command signals for control of assistive devices; deep brain stimulation; and epilepsy detection and intervention.

Schedule

Monday, May 12
8:00-8:45am Welcome reception with continental breakfast
8:45-9:00am Welcome and introduction: Avner Friedman, Dawn Taylor, and Dave Terman
Field-potential-based control of assistive devices
9:00-9:45am Theresa Vaughan: Overview: State of the art of field-potential-based brain-machine interfaces - communication, environmental control, neuroprosthetic control, and rehabilitation therapy
9:45-10:00am Discussion
10:00-10:45am Chuck Anderson: Signal processing and Classifier functions for EEG-based brain machine interfaces
10:45-11:00am Discussion
11:00-11:45am Gerwin Schalk: Continuous movement control with field potentials
11:45-12:00pm Discussion
12:00-1:30pm Lunch break
1:30-2:15pm Femke Nijboer: Moving brain-machine interfaces into people's homes
2:15-2:30pm Discussion
2:30-4:00pm Workgroup discussions on moving the field forward
4:00-4:30pm Break
4:30-5:30pm Short talks (15 minutes each) by additional participants
Tuesday, May 13
Spike sorting and tracking for real-time applications
8:30-9:15am Dawn Taylor: Overview of Multichannel Sorting Algorithms
9:15-9:30am Discussion
9:30-10:15am Carlos Vargas: Automated Spike Sorting for large datasets using Density Grid Contour Clustering
10:15-10:30am Discussion
10:30-11:15am TBD: Neuron Signature Based Spike Sorting for Realtime Applications
11:15-11:30pm Discussion
11:30-1:00pm Lunch break
1:00-1:30pm Karim G. Oweiss: Optimizing spike sorting efficiency in hardware
1:30-3:00pm Workgroup discussions on moving the field forward
Multi-channel microelectrode-based control of Devices
3:00-3:30pm Karim Oweiss: Engineering Large Scale Interfaces to the Brain: Can We Electronically Read the Mind?
3:30-3:45pm Discussion
3:45-4:30pm Lee Miller: Decoding direct muscle activity and feedback control
4:30-4:45pm Discussion
4:45-5:30pm Break
5:30-6:30pm Eb Fetz public lecture on real-time neural interfacing and BCIs
6:30pm Reception: in Jennings Hall, 3rd Floor
Wednesday, May 14
Multi-channel microelectrode-based control of Devices (continued)
8:30-9:15am Leigh Hochberg: Neural interfaces for the restoration of communication and mobility - early clinical trial experience
9:15-9:30am Break
9:30-10:15am Daniel W. Moran: High Frequency Local Field Potentials for BCI Control
10:15-10:30am Discussion
10:30-11:15am Dawn Taylor: Learning effects and design of adaptive decoders
11:15-11:30pm Discussion
11:30-1:00pm Lunch break
1:00-1:45pm Justin Sanchez: Continuous decoding of intracortical signals
1:45-2:00pm Discussion
2:00-3:30pm Workgroup discussions on moving the field forward
3:30-4:00pm Break
Neural Analysis for real-time epilepsy interventions and neuromodulation
4:00-4:45pm TBD
4:45-5:00pm Discussion
5:00-5:45pm Short talks (15 minutes each) by additional participants
6:00-9:00pm Banquet dinner at Holiday Inn on the Lane
Thursday, May 15
Neural Analysis for real-time epilepsy interventions and neuromodulation (continued)
8:30-9:15am Klaus Lehnertz: Epileptic Seizure Prediction: State-of-the-Art and Future Requirements
9:15-9:45am Discussion
9:45-10:30am Robert B. Duckrow: Responsive Neurostimulation for Epilepsy
10:30-11:15am Discussion
11:15-12:15pm 15 minute mini talks by additional participants
12:15 -1:45pm Lunch break
1:45-2:30pm Brian Litt: Applied interventions and assessment issues
2:30-3:00pm Discussion
3:00-4:00pm Workgroup discussions on moving the field forward
4:00-5:00pm Wrap up and final discussion