Schedule |
| Monday, June 8 |
| Whole-Genome Analysis |
| 8:00am |
Shuttle leaves for MBI |
| 8:50-9:00am |
Welcome, overview of workshop, and introductions: Marty Golubitsky, Hans Othmer and Mike Levine |
| 9:00-9:45am |
Julia Zeitlinger: Evolution of the DV transcriptional regulatory network in closely related Drosophila species |
| 9:45-10:30am |
Lior Pachter: Drosophila genome dynamics at the nucleotide level |
| 10:30-10:45am |
Break |
| 10:45-11:30am |
Norbert Perrimon: Large scale analyses of signaling networks |
| 11:30-12:15pm |
Eileen Furlong: Transcription factor binding reveals spatial and temporal aspects of developmental networks |
| 12:15-2:00pm |
Lunch break |
| 2:00-2:45pm |
Tom Kornberg: Mechanisms of morphogen dispersion and action |
| 2:45-3:30pm |
Manolis Kellis: Regulatory genomics of Drosophila tissue- and stage-specific gene expression patterns |
| 3:30-3:45pm |
Break |
| 3:45-4:30pm |
Alexander Stark: Comparative genomics of gene regulation in Drosophila |
| 4:30-6:30pm |
Reception in the MBI Lounge |
| 6:30pm |
Shuttle pick-up MBI |
| Tuesday, June 9 |
| Basic Mechanisms |
| 8:00am |
Shuttle leaves for MBI |
| 9:00-9:45am |
Edwin Ferguson: Positive feedback underlies the spatial bistability of Dpp - receptor interactions during dorsal-ventral patterning in the Drosophila embryo |
| 9:45-10:30am |
Haini Cai: The Drosophila SF1 chromatin boundary may regulate enhancer-promoter interactions by organizing dynamic chromatin loop domains |
| 10:30-11:00am |
Break |
| 11:00-11:45am |
Claude Desplan: Stochastic choices in the Drosophila eye |
| 11:45-1:45pm |
Lunch break |
| 1:45-2:30pm |
Seth Blair: Crossveins and the extracellular regulation of BMP signaling |
| 2:30-3:15pm |
David Arnosti: Mechanisms and regulatory grammar of short- and long-range repressors |
| 3:15-3:30pm |
Break |
| 3:30-4:15pm |
Arthur Lander: Constraints, tradeoffs and complexity in morphogen-mediated patterning |
| 4:15-5:00pm |
David Umulis: Organism-scale modeling of early Drosophila patterning via Bone Morphogenetic Proteins |
| 5:30pm |
Shuttle pick-up from MBI |
| Wednesday, June 10 |
| Modeling |
| 8:00am |
Shuttle leaves for MBI |
| 9:00-9:45am |
John Reinitz: When Two Plus Two Doesn't Equal Four: Modeling Non-Modular Enhancer Behavior in the eve Promoter |
| 9:45-10:30am |
Ben Shilo: Robustness and scaling of morphogen patterning in Drosophila and Xenopus embryos |
| 10:30-11:00am |
Break |
| 11:00-11:45am |
Maria Samsonova: Variation and canalization of gene expression in the Drosophila blastoderm |
| 11:45-1:45pm |
Lunch break |
| 1:45-2:30pm |
Reka Albert: Lessons from modeling Drosophila segment polarity: robustness of gene regulatory networks |
| 2:30-2:45pm |
Break |
| 2:45-3:30pm |
Hamid Bolouri: Reconstructing condition-specific gene regulatory interactions in the absence of perturbation data |
| 4:00pm |
Shuttle pick-up from MBI |
| Thursday, June 11 |
| Gene Networks in Development |
| 8:00am |
Shuttle leaves for MBI |
| 9:00-9:45am |
Stephen Small: Bicoid-dependent embryonic patterning in Drosophila |
| 9:45-10:30am |
Angela Stathopoulos: Patterning a field of cells: a comparison of dorso-ventral patterning of the embryo and anterior-posterior patterning of the wing disc |
| 10:30-11:00am |
Break |
| 11:00-11:45am |
Stephen Crews: The Regulation of Drosophila CNS Midline Neuronal and Glial Development and Transcription |
| 11:45-12:30pm |
Maria Leptin: From dorso-ventral patterning to cell shape changes |
| 12:30-2:30pm |
Lunch break |
| 2:30-3:15pm |
Hans Othmer: Robustness of Pattern Formation in Development |
| 3:15-3:30pm |
Break |
| 3:30-4:15pm |
Stanislav Shvartsman: MAPK substrate competition in the Drosophila embryo |
| 5:00pm |
Shuttle pick-up from MBI |
| Friday, June 12 |
| Topology and Logic of Gene Networks |
| 8:00am |
Shuttle leaves for MBI |
| 9:00-9:45am |
Christine Rushlow: Zelda, a key activator of the early zygotic genome in Drosophila |
| 9:45-10:30am |
Manfred Frasch: Transcriptional and signaling networks during mesodermal tissue development in Drosophila |
| 10:30-11:00am |
Break |
| 11:00-11:45am |
Mike Levine: Transcriptional precision in the Drosophila embryo |
| 11:45-12:30pm |
Albert Erives: Gene regulatory evolution in an equivalence class of developmental enhancers |
| 1:30pm |
Shuttle pick-up to hotel |