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Workshop 2: Dynamics of signal transduction and of gene-protein regulatory networks: Schedule

Schedule

Monday, November 2
Signal transduction networks
8:00am Shuttle leaves for MBI
8:45-9:00am Welcome, overview of workshop, and introductions: Marty Golubitsky and organizers
9:00-10:00am Andre Levchenko: Tutorial
10:00-10:30am Break
10:30-11:30am Jason Haugh: Dynamic Regulation of the PDGF Receptor Signaling Network
11:30-1:30pm Lunch break
1:30-2:30pm Liwu Li: Positive and Negative Molecular Signaling Networks Controlling the Fate of Macrophages
2:30-3:00pm Break
3:00-4:00pm Tim Elston: A systems biology analysis of yeast chemotrophic growth
4:00-5:00pm Victor Sourjik: Noise, robustness and memory in bacterial chemotaxis
5:00pm

Reception & Poster session:
- Sandip Kar: Exploring the roles of noise in the eukaryotic cell cycle
- Zhanghan Wu: Amplification and Detection of Single-Molecule Conformational Fluctuation through a Protein Interaction Network with Bimodal Distributions
- Baris Hancioglu: The Dynamics of Exit from Mitosis in Budding Yeast
- Debashis Barik: Bistability by Multiple Phosphorylation of Regulatory Proteins
- James Lu: Mapping dynamics to mechanisms: qualitative inverse problems in biology
- Yongfeng Li: A mathematical study of Goldbeter-Koshland model for open signaling cascade with forward activation
- Assieh Saadatpour-Moghaddam: Attractor analysis of asynchronous Boolean models of signal transduction networks
- Ruisheng Wang: Boolean modeling of microarray data reveals novel modes of heterotrimeric G protein action
- Colin Campbell: A Generalized Model of Immune-Surveillance of Tissue Specific Tumors
- Dirk van Zwieten: Discrete event modeling: Glycolysis and energy balance
- Jon Young: A Simplified Ras-Raf-Mek-Erk Pathway with a Single GFR
- Jianhua Xing: Systems biology and nonequilibrium statistical physics

7:00pm Shuttle pick-up from MBI
Tuesday, November 3
Gene regulatory networks
8:00am Shuttle leaves for MBI
9:00-10:00am James Liao: Resistance to Diet-Induced Obesity
10:00-10:30am Break
10:30-11:30am Zoltan Oltvai: An integrated approach for drug development and customized therapy
11:30-1:30pm Lunch break
1:30-2:30pm Leor Weinberger: An Endogenous Gene Expression Level-to-Rate Converter Provides a Fitness Advantage
2:30-3:00pm Break
3:00-4:00pm Guy Shinar: Structural sources of robustness in biochemical reaction networks
4:00-5:00pm

Contributed talks (15 minutes + 5 minute Q&A):
-Oleg Igoshin: Multiple positive feedbacks lead to bistability and low-pass filtering in gene regulatory network module controlling hematopoiesis
-Christian Darabos: Are cells really operating at the edge of chaos? A case study of two real-life regulatory networks
-Jaewook Joo: Stochastic and heterogeneous dynamical response of NF-kB upon Lipopolysaccharide insult to live macrophages

5:30pm Shuttle pick-up from MBI
Wednesday, November 4
Modeling approaches
8:00am Shuttle leaves for MBI
9:00-10:00am Reka Albert: Discrete dynamic modeling of signal transduction networks: Survival signaling in T-LGL leukemia
10:00-10:30am Break
10:30-11:30am Jehoshua Bruck: Random Ideas About Biology
11:30-1:30pm Lunch break
1:30-2:30pm Karen Sachs
2:30-3:00pm Break
3:00-4:00pm Ilya Nemenman: Phenomenological models of regulatory networks
4:00-5:00pm Marty Golubitsky: Patterns of Oscillations in Coupled Systems
5:30pm Shuttle pick-up from MBI
Thursday, November 5
Gene regulation in development
8:00am Shuttle leaves for MBI
9:00-10:00am Leah Keshet: Modeling cell polarity and motility: signaling to actin
10:00-10:30am Break
10:30-11:30am Stanislav Shvartsman
11:30-1:30pm Lunch break
1:30-2:30pm John Tyson: Stochastic Models of Cell Cycle Regulation in Eukaryotes
2:30-3:00pm Break
3:00-4:30pm

Contributed talks (15 minutes + 5 minute Q&A):
-Richard Yamada: Molecular Noise Enhances Oscillations in the Supra-Chiasmatic Nuclei Network
-Shinya Kuroda: Temporal coding of Akt signaling networks
-Attila Csikasz-Nagy: Role of protein removal in signaling
-Dieter Armbruster: Dynamic Simulations of Single-Molecule Enzyme Networks

5:00pm Shuttle pick-up from MBI
6:00pm Cash Bar
7:00pm Banquet
Friday, November 6
Cell cycle
8:00am Shuttle leaves for MBI
9:00-10:00am Frederick Cross
10:00-10:30am Break
10:30-11:30am Joe Pomerening: Elucidating the Architecture of the CDK1-APC Oscillator
12:00pm Shuttle pick-up from MBI