This year the program will focus on Cell Processes. The program leader is Professor James Sneyd. After an introductory tutorial and discussion in the first two days, the participants will be divided into teams of five, with each team being led by an MBI postdoc. Teams will work on one project for the first two and a half weeks, and there will be a miniconference in the final two days.
During the three-week period there will also be several general talks on cell cycle and proliferation by active researchers and visits to bioscience labs.
|Monday, August 2|
|9:00-9:05am||Welcome (Avner Friedman)|
|9:05-10:05am||James Sneyd: Enzyme kinetics - PPT|
|10:30-11:30am||James Sneyd: How cells control their volume - PPT|
|2:00-3:00pm||Martin Wechselberger: Introduction to Dynamical Systems: Phase analysis and bifurcation|
|3:00-4:00pm||Pranay Goel: Introduction to XPP|
|Tuesday, August 3|
|9:00-10:00am||James Sneyd: Calcium physiology - PPT|
|10:30-11:30am||James Sneyd: Cardiac electrical physiology - PPT|
|1:30-2:00pm||Martin Wechselberger: Introduction to Dynamical Systems (continued)|
|2:00-3:00pm||Pranay Goel: XPP (continued)|
|3:30-5:30pm||Project leaders describe their projects.||Wednesday, August 4|
|9:00-10:00am||Participants write their preferred projects|
|10:00am||Teams are selected and begin work, guided by their project leaders||Thursday, August 5|
|9:00-10:00am||Gustavo Leone: Cellular Differentiation and Cancer - PPT1||Friday, August 6|
|9:00-10:00am||Gustavo Leone: Cellular Differentiation and Cancer - PPT2|
|Tuesday, August 10|
|1:00-2:00pm||Andrea Doseff: Apoptosis I||Wednesday, August 11|
|1:00-2:00pm||Andrea Doseff: Apoptosis II|
|2:00-4:00pm||Andrea Doseff: Lab||Thursday, August 12|
|1:00-2:00pm||Berl Oakley: Gamma-tubulin functions in microtubule nucleation and cell cycle regulation|
|2:00pm||Berl Oakley: Lab||Friday, August 13|
|4:00pm||Gustavo Leone: Lab|
Project 1: Calcium and Heart Failure
Project Leader: Pranay Goel
Construct a model for a calcium transient in a normal ventricular myocyte, and in heart failure cells that explain the differences in the calcium transients. How does your model cope with calcium overload?
Project 2: Synaptic Plasticity
Project leader: Alla Borisyuk
Synaptic transmission and synaptic plasticity.
Project 3: Cell Cycle and Apoptosis
Project leader: Gheorghe Craciun
Construct a model that couples cell cycle and apoptosis.
Project 4: Olfaction
Project leader: Daniel Dougherty
Construct a model of a signal transduction and adaptation in odoreceptors.
Project 5: Calcium Oscillations
Project leader: Martin Wechselberger
Design a realistic experimental protocol that will determine the role of [IP3] in Ca2+ oscillations in pancreatic acinar cells.