A computational model of the mechanics of growth of a trophoblast tissue

Katarzyna Rejniak
Mathematical Biosciences Institute, The Ohio State University

(October 23, 2002 12:30 PM - 1:30 PM)

A computational model of the mechanics of growth of a trophoblast tissue

Abstract

Results of clinical research show strong connections between appearance of deep invaginations of the trophoblast tissue and pregnancy complications. Because the trophoblast tissue grows only by cell proliferation and fusion, it is important to analyse how the initiation of these processes can cause the tissue to bend. In my talk, I will show how the trophoblast tissue can be modeled using the immersed boundary method and will present simulations of tissue development, along with comparisons with clinically obtained results.