Network motifs and complex tissues

Dan Siegal-Gaskins
Mathematical Biosciences Institute (MBI), The Ohio State University

(September 16, 2010 10:30 AM - 11:30 AM)

Network motifs and complex tissues

Abstract

Characterization of the intricate gene regulatory networks that govern organism behavior has led to the discovery a number of small and topologically distinct subnetworks known as 'network motifs'. Along with experimental efforts, dynamical systems modeling has provided new insights into the equilibrium states and transient dynamics of such subnetworks. In this talk I will give a brief overview of some of the more biologically-relevant motifs, detail the successes of the systems biological approach to motif identification, and discuss some of the challenges to the study of network motifs in complex organisms.