Multiscale Modeling of Hematological Disorders

George Karniadakis
Department of Applied Mathematics, Brown University

(May 23, 2011 2:30 PM - 3:30 PM)

Multiscale Modeling of Hematological Disorders

Abstract

I will first present recent developments on the Dissipative particle Dynamics (DPD) -- a Lagrangian method that bridges the gap between continuum and atomistic scales. In particular, I will first discuss theoretical foundations of DPD, its relation to molecular dynamics (MD), and its use in modeling seamlessly blood flow interacting with blood cells (platelets, white cells and red blood cells (RBCs). Specific examples will be given for cerebral malaria and sickle cell anemia.

This work is supported by NIH and by the DOE/INCITE program and NSF/NICS for computations.