Use noise to determine cardiac restitution with memory

Shu Dai
MBI - Postdoc, The Ohio State University

(May 5, 2011 10:30 AM - 11:30 AM)

Use noise to determine cardiac restitution with memory

Abstract

Noise in cardiac pacing cycles, for instance, the heart rate variability, has been observed and researched for decades. Contemporarily, various cardiac models have been constructed to investigate the electric activity of the cardiac cells. Yet there has not been a study on extracting information of the underlying dynamics if some noisy data are given. In this talk we will show a method to determine the cardiac restitution approximately in the range of the pacing cycles provided a series of noisy data. We assume the data are generated through some unknown mapping model with memory, and the memory is supposed to be hidden and not able to be detected.