Fall 2013 Course: Introduction to genomic methods to answer biological questions

Helen Chamberlin
Molecular Genetics, The Ohio State University

(September 6, 2013 10:20 AM - 11:15 AM)

Fall 2013 Course: Introduction to genomic methods to answer biological questions

Abstract

Recent innovations have allowed researchers and clinicians to determine the complete sequence of DNA and RNA samples from individuals and even populations rapidly and cheaply.  These methods are revolutionizing the types of biological questions that experimentalists can ask, and the types of datasets available for computational analysis.  This course will provide an introduction to these methods and their biological applications.  Course participants will use class discussion and readings from the research literature to identify how laboratory researchers apply these methods, and to recognize the strengths and the limitations of genomic approaches.

 

Topics will include: Genes and their impact on biological traits Large scale sequencing methods Whole genome analysis:     comparative genomics     metagenomics     GWAS Analysis of genomic activity:     Chromatin Immunoprecipitation     mRNA analysis     microRNA analysis     ribosome profiling