Upcoming Colloquia

All seminars will be held in the MBI Lecture Hall - Jennings Hall, Room 355 - unless otherwise noted.

September 22, 2014 3:00 - 3:50PM
Host: Dr. Shili Lin

This talk will cover the convergence of two high profile themes in the scientific/medical literature (and even the lay press): personalized medicine and lack of reproducibility of scientific results. There have been many high profile examples of scientific findings related to genetic (or more generally) biomarker predictors of disease or drug effect that have not been confirmed with subsequent experimentation or investigation. Some recent literature suggests that inappropriate use of statistical analysis or inadequate use of statistical design principles play a major role in false positive findings. This talk will address the use of Bayesian statistical principles for how to assess the strength of evidence for a finding and how that can be applied generally to clinical trials and laboratory research. 

 

*        Likelihood of truth

**      Any biological measurement to describe a patient

***    AKA personalized medicine, precision medicine, targeted medicine

 
October 06, 2014 3:00 - 3:50PM
Host: Charles Bell

Evolutionary relationships (i.e., homology) detected between proteins helps predict their properties such as spatial structures and functions. Homology is frequently obscured by sequence divergence, spatial structure changes and resemblance between unrelated 3D structures. Computational approaches to the analysis of distant homologs and their discrimination from proteins with fortuitous similarities will be discussed and examples of how this theoretical and bioinformatics work facilitates experimental discoveries will be given.

TBA
October 20, 2014 3:00 - 3:50PM
Host: Avner Friedman

TBA

TBD
October 27, 2014 3:00 - 3:50PM
Host: Erich Grotewold

Abstract coming soon.

TBD
November 10, 2014 3:00 - 3:50PM

Abstract Not Submitted.

TBD
November 10, 2014 3:00 - 3:50PM

Abstract Not Submitted

TBD
December 01, 2014 3:00 - 3:50PM
Host: Andrej Rotter

Abstract coming soon.

TBD
February 09, 2015 3:00 - 3:50PM
Host: Andrej Rotter

Abstract coming soon.