Upcoming Colloquia

All seminars will be held in the MBI Lecture Hall - Jennings Hall, Room 355 - unless otherwise noted.

January 26, 2015 3:00 - 3:50PM
Host: Soledad Fernandez

Motivated by data from multiple randomized trials of colon cancer, we model time-to-cancer-recurrence and time-to-death using a multi-state model. We incorporate a latent cured state into the model to allow for subjects who will never recur. Parametric models that assume Weibull hazards and include baseline covariates are used. Information from the multiple trials are included using a hierarchical model. Bayesian estimation methods are used. The model is used to assess whether there is improved efficiency in the analysis of the effect of treatment on time-to-death in each trial by using the information provided by earlier cancer recurrence. For subjects who are censored for death, multiple imputation is used to impute death times, where the imputation distribution is derived from the estimated model. Gains in efficiency are possible, although sometimes modest, using the extra information provided by the recurrence time.

TBD
February 23, 2015 3:00 - 3:50PM
Host: TBD

Abstract not submitted.

TBD
March 02, 2015 3:00 - 3:50PM
Host: TBD

Abstract not submitted.

TBD
March 09, 2015 3:00 - 3:50PM
Host: TBD

Abstract not submitted.

TBD
April 06, 2015 3:00 - 3:50PM
Host: TBD

Abstract not submitted.

TBD
April 20, 2015 3:00 - 3:50PM
Host: TBD

Abstract not submitted.