Neurogenesis allows olfactory bulb to learn to decorrelate stimuli

Hermann Riecke

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Abstract

The olfactory bulb exhibits substantial turn-over of the dominant interneuron population, even in adult animals. It is observed that with neurogenesis suppressed the animals' capacity for perceptual learning is impaired. We have developed a simple network model in which the connectivity adapts to the odor environment through the experimentally observed dependence of the survival of the interneurons on their activity. Due to the reciprocity of the connections between the principal neurons and the interneurons this restructuring of the network allows it to reduce the correlation of the representations of similar stimuli.