Modelling and inference for healthcare-associated infection

Philip O'Neill (March 20, 2012)

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Multi-drug resistant pathogens such as MRSA and VRE give rise to substantial morbidity and mortality, and impose a huge economic burden on healthcare systems. In this talk we describe a framework for analysing patient-level data from hosptials on such pathogens, employing stochastic transmission models and using Markov chain Monte Carlo methods witin a Bayesian statistical framework. The methods are illustrated with various data sets and used to address various clinically-relevant questions.