MBI Videos

Videos by CTW: Mathematical and Computational Challenges in Cilia- and Flagella-Induced Fluid Dynamics

  • Afternoon Blitz Session Talk (10-15-2012) (Arezoo Ardekani)
    Arezoo Ardekani
    Blitz Session (Arezoo Ardekani)...
  • Modeling Hyperactivated Sperm Motility
    Sarah Olson
    Sperm are known to exhibit two distinct types of motility. One is characterized by constant amplitude, symmetrical waveforms. The other is characterized by asymmetrical waveforms, which are correlated with an increase in calcium concentration. The goal of this work is to model the undulatory swimming of sperm swimming in a viscous, incompressible fluid using the method of ...
  • Cilia in the Development of Left-right asymmetry
    Martina Brueckner
    Cilia in the Development of Left-right asymmetry...
  • Afternoon Blitz Session Talk (10-15-2012) (Rich Superfine)
    Rich Superfine
    Blitz Session Talk (Rich Superfine)...
  • Engineered microswimmers and micropumps
    Marc Fermigier
    Since the pioneering studies of GI Taylor in the fifties, models have been used to gain understanding in the propulsion of microorganisms. Modern microfabrication techniques enable us to assemble very small scale devices emulating the motion of cilia. I will review the different strategies used in recent years towards the goal of fabricating micron scale artificial swimmer...
  • Sensitivity of cilia-induced transport to fluid rheology, axoneme structure, and dynein forcing
    Sorin Mitran
    A fluid-structure interaction model that couples viscoelastic fluid motion induced by collective behavior of cilia to detailed axoneme mechanics is used to investigate bounds on cilia structure and mucus properties that determine effective fluid clearance. Dynein forcing is represented by a stochastic walker model that responds to local ATP concentrations provided by a bio...
  • Helical bodies swim slower... and faster... through a viscoelastic fluid
    Saverio Spagnolie
    Many microorganisms swim by rotating one or many helical flagella, often propelling themselves through fluids that exhibit both viscous and elastic qualities in response to deformations. In an effort to better understand the complex interaction between the fluid and body in such systems, we have studied numerically the force-free swimming of a rotating helix in a viscoelas...
  • Hydrodynamic Synchronization, Coordination, and Signalling
    Ramin Golestanian
    Microorganisms and the mechanical components of the cell motility machinery such as cilia and flagella operate in low Reynolds number conditions where hydrodynamics is dominated by viscous forces. The medium thus induces a long-ranged hydrodynamic interaction between these active objects, which could lead to synchronization, coordination and other emergent many-body behavi...
  • Computational models of ciliary dynamics: successes and challenges
    Lisa Fauci
    The beating of a cilium is an elegant example of an actuated elastic structure coupled to a surrounding fluid. Computational fluid dynamics enthusiasts will recognize that ciliary systems present many complications such as the interaction of groups of cilia, the influence of boundaries, and the coupling to fluids that have complex rheology and microstructures. Moreover, th...
  • Ciliary Motility- outside and inside
    Karl Lechtreck
    The ventricular system in the brain is lined by multiciliated cells. The motility of these ependymal cilia was analyzed in hy3-/- mice which carry a null mutation in Hydin and develop lethal hydrocephalus. Hy3-/- cilia lack a projection from the ciliary central pair and move with slightly reduced beat frequency and a greatly reduced beat amplitude. They lack the ability to...

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