2016 SUMMER UNDERGRADUATE REU PROGRAM

Arizona State University

ASU - School of Mathematical and Statistical Sciences

Topic 1:

Modeling Prostate Cancer Treatment - Fabio Milner, Abba Gumel, and Yang Kuang

Students will work on the design, refinement, and numerical simulation of models of prostate cancer treatment, including Intermittent Androgen Suppression (IAS) therapy and Zytega for advanced stages, and compare several models in their predictive power using a real-life dataset from a long-term study in Canada and an ongoing one at the Mayo clinic. Participants will learn to model biological interactions using dynamical systems; implement parameter identification techniques from real-life data; and discover why such problems are often ill-posed. Matlab will be used to estimate parameters and simulate the dynamics of the system under study.