MBI Videos

Videos by 2010 Workshop for Young Researchers in Mathematical Biology

  • Algebraic models in systems biology
    Reinhard Laubenbacher
    Progress in systems biology relies on the use of mathematical and statistical models for system level studies of biological processes. Several different modeling frameworks have been used successfully, including traditional differential equations based models, a variety of stochastic models, agent-based models, and Boolean networks, to name some common ones. This talk will...
  • Kinesin-Microtubule Interactions: Transport and Spindle Formation
    Peter Bates
    This talk consists of two parts: Pattern formation in families of microtubules under the action of kinesin and the detailed motion of kinesin along a microtubule.

    Microtubules are long cylindrical structures (lengths being tens of microns and diameter approximately 25 nm) comprised of tubulin dimers, which self-assemble, 13 protofilaments being required side...
  • Asymmetric stable droplets in a fish patterning model.
    Thomas Woolley
    Soliton like structures called "stable droplets" are found to exist within a paradigm reaction diffusion model which can be used to describe the patterning in a number of fish species. It is straightforward to analyse this phenomenon in the case when two non-zero stable steady states are symmetric, however the asymmetric case is more challenging. We use a recentl...
  • Evolution of body size in food webs
    Rosalyn Rael
    Body size has been shown to be a significant factor in shaping the structure of food webs, which are network models of the flow of energy in an ecosystem. Recent studies have shown that body size constraints can influence food web dynamics through prey preference and foraging behavior, and can thereby influence the stability of these ecosystem models. Because of its signif...
  • Modeling Neural Circuitry for Early Olfactory Processing
    William Sherwood
    The neuronal networks of the olfactory system transduce and transform complex mixtures of odorant molecules into patterns of the neural activity representing smells. We explore two important aspects of how this process works, at the cellular and the neural circuit level, in modeling studies that produce experimental testable predictions.

    1) It has long been ...
  • Scaling in Vascular Networks: Curvature, Finite-Size Effects, and Applications to Tumor Angiogenesis and Growth
    Van Savage
    Metabolic rate, heart rate, and lifespan depend on body size according to scaling relationships that extend over ~21 orders of magnitude and that represent diverse taxa and environments. These relationships for body mass have long been approximated by power laws, but there has been intense debate about the values of exponents (e.g., 1/4 versus 1/3). I will show for mammals...

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