Seminar: Colin Klaus - Multiscale Approaches in Visual Transduction: A New Homogenized Diffusion Model for Cone Photoreceptors in Bright Light

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December 3, 2019
10:20AM - 11:15AM
Location
MBI Auditorium, Jennings Hall 355

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Add to Calendar 2019-12-03 10:20:00 2019-12-03 11:15:00 Seminar: Colin Klaus - Multiscale Approaches in Visual Transduction: A New Homogenized Diffusion Model for Cone Photoreceptors in Bright Light

Colin Klaus

Postdoctoral Fellow, MBI


Mammals have two types of photoreceptors, rods and cones. While rods are exceptionally sensitive and mediate vision at very low illumination levels, cones operate in daylight and are responsible for the bulk of visual perception. A recently published 3d model for cone photoreceptors in dim light was made possible by the partial differential equations' techniques of homogenization and concentrated capacity. In this talk I will adapt this model to the case of cone photoreceptors in high intensity light.  Owing to the significant computational speedup afforded by the homogenized model compared to a standard diffusion model (mins/run vs ~20hrs/run), parameter sensitivity analysis both local and global is possible and initial findings will be presented. Some initial comparison with experiments will also be shown.

This talk is free and open to the public.

MBI Auditorium, Jennings Hall 355 Mathematical Biosciences Institute mbi-webmaster@osu.edu America/New_York public
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Colin Klaus

Postdoctoral Fellow, MBI


Mammals have two types of photoreceptors, rods and cones. While rods are exceptionally sensitive and mediate vision at very low illumination levels, cones operate in daylight and are responsible for the bulk of visual perception. A recently published 3d model for cone photoreceptors in dim light was made possible by the partial differential equations' techniques of homogenization and concentrated capacity. In this talk I will adapt this model to the case of cone photoreceptors in high intensity light.  Owing to the significant computational speedup afforded by the homogenized model compared to a standard diffusion model (mins/run vs ~20hrs/run), parameter sensitivity analysis both local and global is possible and initial findings will be presented. Some initial comparison with experiments will also be shown.

This talk is free and open to the public.

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